Effects of 4-Methylpyrazole on Ethanol Neurobehavioral Toxicity in CD-1 Mice
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چکیده
منابع مشابه
Effects of polychlorinated biphenyls in CD-1 mice: reproductive toxicity and intergenerational transmission.
Several studies indicate that in utero and perinatal exposure to polychlorinated biphenyls (PCBs) induces adverse reproductive effects, but it remains unclear whether such effects may be transmitted to subsequent generations. We therefore investigated the association between maternal exposure to PCBs and reproductive health in male and female offspring over three generations. Mouse dams were fe...
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Pyrazole and 4-methylpyrazole, which are inhibitors of alcohol dehydrogenase, were also found to be effective inhibitors of the oxidation of ethanol by liver microsomes (microsomal fractions) in vitro. Ethanol oxidation by microsomes from rats previously treated for 2 or 3 days with either pyrazole or 4-methylpyrazole appeared to be especially sensitive to inhibition in vitro by pyrazole or 4-m...
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Introduction: - Significant increase in usage of silver nanoparticles (AgNPs) in consumer products, has increased its exposures to human and animals. Although there are some reports regarding the effects of AgNPs on complex organisms, no report was found as to its effects on neurobehavioral ontogeny. Methods: To investigate the effects of maternal exposure to AgNPs on development of neu...
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Background. Proximal and distal social stimulation increase ethanol drinking in humans. Purpose. Our study evaluated the effects of proximal and distal social stimulation on home-cage ethanol drinking in mice. Study design. Proximal cagemate drinking (PCD) procedures use a clear plastic barrier to separate the drinker mouse from the proximal cagemate mouse, to evaluate home-cage drinking of 10%...
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ژورنال
عنوان ژورنال: Academic Emergency Medicine
سال: 2004
ISSN: 1069-6563,1553-2712
DOI: 10.1197/j.aem.2004.03.007